Mohammed “Mo” Amer and Ramy Youssef have been pushing against borders and boundaries, personally and professionally, for as long as they can remember. In their stand-up comedy, Amer and Youssef share experiences from their lives as Arab Americans and Muslim Americans, delivering acerbic jokes about racism and bigotry in one breath, and poking bemusedly at the strictness of religious faith and cultural practice in another. Their overlapping perspectives on immigration, Islam, and identity, coupled with their years of friendship, have also guided their shared TV projects. In Hulu’s Ramy, co-created by and starring Youssef and featuring Amer in the main ensemble, the two challenge the idea of a “good Muslim” with a central tension between the fictionalized Ramy’s self-destructive impulsiveness and his desire to have a closer relationship with God. And with the new Netflix series Mo, which Amer and Youssef developed years ago, the two turn their eyes to loosely adapting Amer’s singular life.